E-cigarettes might not be benign

| April 10, 2014

E-cigarettes can change gene expression in a similar way to that of tobacco, according to a story by Daniel Cressey for Nature quoting one of the first studies to investigate the biological effects of the devices.

Presented at the American Association for Cancer Research’s annual meeting in San Diego, California, USA ,the research looked at human bronchial cells that contained some mutations found in smokers at risk of lung cancer. The cells were immortalized, grown in culture medium that had been exposed to e-cigarette vapor and their gene expression profiled.

The researchers found that the cells grown in medium exposed to the vapor of e-cigarettes showed a similar pattern of gene expression to those grown in a medium exposed to tobacco smoke.

The changes were not identical, said study researcher, Avrum Spira, who works on genomics and lung cancer at Boston University in Massachusetts. But “there are some striking similarities,” he said.

The researchers are now evaluating whether the alterations mean that cells behave more like cancer cells in culture.

The work is at a very early stage and therefore cannot establish that e-cigarettes can cause cancer in vitro, let alone in vivo.

Spira said that the use of e-cigarettes might be safer than the use of tobacco cigarettes, but that the researcher’s preliminary studies suggested that the use of the former might not be benign.

Category: Breaking News

Comments are closed.

Sponsor Ad

Sponsor Ad

Sponsor Ad

Web exclusives

Discussing challenges

Discussing challenges

Tobacco growers convene in Indonesia.

| April 2, 2018
The promise of heated tobacco

The promise of heated tobacco

Peter Nixon, PMI’s U.K. and Ireland MD, praises England’s progressive approach to new technologies.

| February 28, 2018
Celebrating cigars at Puro Sabor

Celebrating cigars at Puro Sabor

Five days of factory tours, farm visits, recreational activities and many, many cigars.

| February 5, 2018
Farmers concerned

Farmers concerned

The ITGA worries about slumping demand for leaf tobacco and a lack of alternative crops

| November 2, 2017
Their fair share

Their fair share

Tobacco growers deserve better

| November 1, 2017
Lease on life

Lease on life

Industry leaders respond to the FDA’s new attitude toward vapor products.

| October 1, 2017
The Vype Dossier

The Vype Dossier

Proving the reduced-risk potential of an e-cigarette

| October 1, 2017

Sponsor Ad

From the leaf lands

Grading system questioned

Grading system questioned

The grading system in Malawi, where yet again leaf tobacco prices are favoring buyers, is said to leave a lot to be desired.

| April 17, 2018
Prices dip to US$0.80 per kg

Prices dip to US$0.80 per kg

Malawi’s tobacco sales season got off to an awful start on Monday with some prices well below a dollar a kg, which far from reflected the work that had gone into producing the leaf.

| April 10, 2018
Prices increased in India

Prices increased in India

The prices paid to flue-cured tobacco growers are up in both Andhra Pradesh, where the selling season has just started, and in Karnataka, where it is about to close.

| April 10, 2018
Flue-cured prices increased

Flue-cured prices increased

By the end of the first nine days of sales on Zimbabwe’s 2018 flue-cured tobacco market, the average grower price was up sharply on that of the 2017 season.

| April 9, 2018
Cry for action on child labor

Cry for action on child labor

Human Rights Watch says that children in Zimbabwe are working under hazardous conditions on tobacco farms to earn money for the necessities of life.

| April 6, 2018
Tariff threats ‘troubling’

Tariff threats ‘troubling’

It is often the cry of businesses and industries that ‘change’ should be warmly embraced because it leads to new opportunities. But change trade tariffs and the reaction is different.

| April 5, 2018

Sponsor Ad

Sponsor Ad

Sponsor Ad